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Heat: list of drugs that promote dehydration


There are many medications that can contribute to dehydration during hot weather. The French consumer defense association UFC-Que Choisir draws up a list of the drugs most often implicated.

Dehydration is linked to losses of water and mineral salts that are not compensated by water consumption and food.

Dehydration is a particular threat to young children and the elderly.

In periods of high heat, a reduction in the doses of these medications, or even a temporary or permanent cessation, can be discussed with your attending physician in addition to other preventive measures.»

Medications can promote dehydration through various mechanisms. The list drawn up by the association presents those who are most commonly involved. She is not exhaustive.

Medicines that increase the loss of water and mineral salts

Diuretics (which increase urine production)

Amiloride (Modamide)
Bumetanide (Burinex)
Furosemide (Lasix)
Hydrochlorothiazide (Esidrex and in many antihypertensives)
Indapamide (Fludex)
Spironolactone (Aldactone)
Laxatives (exposing to diarrhea)
Bisacodyl (Dulcolax)
Lactulose (Duphalac)
Macrogol (Forlax, Transipeg)
Senna (Agiolax, Modane)
Antibiotics (exposing to diarrhea)
Amoxicillin (Clamoxyl, Augmentin)
Azithromycin (Zithromax)
Ciprofloxacin (Ciflox)
Doxycycline (Tolexine)

Drugs that impair kidney function

Nonsteroidal anti-inflammatory drugs

Acetylsalicylic acid (Aspirin)
Diclofenac (Flector, Voltarene)
Ibuprofen (Advil, Antarene, Nurofen, Spedifen)
Ketoprofen (Bi-Profenid)
Naproxen (Antalnox, Apranax)
Piroxicam (Feldene)

ACE inhibitors, used against hypertension

Captopril (Lopril)
Enalapril (Renitec)
Fosinopril (generic brands)
Lisinopril (Zestril)
Perindopril (Coversyl)
Ramipril (Triatec)

Sartans, used against hypertension

Candesartan (Atacand)
Irbesartan (Aprovel)
Losartan (Cozaar)
Olmesartan (Olmetec)
Valsartan (Nisis,Tareg)

Drugs that expose to hyperthermia

Thyroid hormones

Levothyroxine (Levothyrox, L-Thyroxin Henning, Thyrofix, TCaps, Euthyral)
Liothyronine (Cynomel)

Neuroleptics, prescribed in psychiatry

Aripiprazole (Abilify)
Clozapine (Leponex)
Cyamemazine (Tercian)
Haloperidol (Haldol)
Loxapine (Loxapac)
Olanzapine (Zyprexa)
Quetiapine (Xeroquel)
Risperidone (Risperdal)


Citalopram (Seropram)
Duloxetine (Cymbalta)
Fluvoxamine (Floxyfral)
Milnacipran (Ixel)
Moclobemide (Moclamine)
Sertraline (Zoloft)
Venlafaxine (Effexor)

Drugs that increase sweating

Drugs prescribed in dementia and myasthenia gravis

Ambenonium (Mytelase)
Donepezil (Aricept)
Galantamine (generic brands)
Memantine (Ebixa)
Pyridostigmine (Mestinon)
Rivastigmine (Exelon)

Other drug classes

Other classes of drugs can increase the effects of extreme heat, such as certain treatments for migraine, Parkinson’s disease, glaucoma or prescribed in cardiology (beta-blockers, digoxin), etc.“, mentions the UFC-Que Choisir. “Consult the instructions.»

For more information, see the links below.

Psychomedia with source: UFC-Que Choisir.
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